Tuberculation is a major form of corrosion on steel and cast iron contacting oxygenated water. Yet, the tuberculation process is not completely understood. Tubercles are much more than amorphous lumps of oxide covering localized areas of metal loss. Structure and chemical composition are complex. Major factors controlling growth include water chemistry, flow and biological interaction. Tubercle structures, chemical composition, growth mechanisms and biological interactions are thoroughly discussed. The relationship between structure and composition illustrates rapid and slow growth.

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